Five Restylane Fillers and When to Use Them

The Restylane line of dermal fillers offers multiple formulations to suit a variety of needs. All of the Restylane fillers feature hyaluronic acid, a naturally-occurring molecule in the body. Hyaluronic acid provides moisture and elasticity to the skin for a youthful, radiant glow.

At Ultimate Image Cosmetic Medical Center in Clearwater, Florida, we offer a full range of Restylane cosmetic treatments. Here, we’ll cover the difference between five Restylane fillers so that you can find the best option for you. 


Restylane is the original hyaluronic acid dermal filler in this line. It’s designed to add volume and fullness to the skin to minimize the appearance of moderate to severe facial wrinkles and folds. Additionally, Restylane is an FDA-approved treatment for lip enhancement.

Restylane Silk

Restylane Silk is designed especially for lip augmentation and smoothing lines around the mouth. It’s a treatment for patients over 21 struggling with lip thinning, lost lip shape, and vertical lines above the lip. 

The Restylane Silk formula is different from other Restylane products because it features smaller, smoother hyaluronic acid particles. This formula is ideal for the delicate lip area.

Restylane Lyft

Restylane Lyft is designed for the treatment of lost volume in the cheeks and hands. In fact, with Restylane Lyft, you can have your face and hands treated in a single session. 

Restylane Lyft with Lidocaine is also available for deep implantation into the facial tissue. This formula is appropriate for moderate to severe facial wrinkles and folds, as well as midface contour deficiencies in patients over 21. 

Restylane Refyne

Restylane Refyne is designed for mid-to-deep injection into the facial tissue to treat moderate to severe facial wrinkles and folds. In particular, this filler can minimize the appearance of nasolabial folds and marionette lines, which become more visible as skin loses its elasticity over time.

Restylane Refyne includes XpresHAn Technology. This cutting-edge innovation in dermal fillers makes for a smoother gel to support natural-looking results. Additionally, the cross-linking in Restylane Refyne gel supports your facial expressions so that the muscles in your face move naturally.

Restylane Defyne

Similarly to Restylane Refyne, Restylane Defyne is intended for mid-to-deep injection into the facial tissue to treat moderate to severe facial wrinkles and folds. However, Restylane Defyne is best used to treat smile lines. 

Restylane Defyne also features XpresHAn Technology to correct deep facial lines, as well as cross-linking in the gel formula to support facial expressions. 

The five Restylane products listed above are used to counteract a range of cosmetic concerns. Depending on your skin type and treatment goals, one of our specialists at Ultimate Image Cosmetic Medical Center in Clearwater will help you determine which option is right for you.